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Hydrocodone: Timeline

  
  

  • 1895: There are several conflicting views concerning the US availability of cough preparations containing ethylmorphine (also called dionine or codethyline) — Feco Syrup and its equivalents were first marketed circa 1895 and still in common use in the 1940s and 1950s, and the main ingredient is treated like codeine under the Controlled Substances Act of 1970. - Hydrocodone, Wikipedia.
  • 1920: Hydrocodone was first synthesized in Germany in 1920[1] and was approved by the Food and Drug Administration on 23 March 1943 for sale in the United States and approved by Health Canada for sale in Canada under the brand name Hycodan. - Hydrocodone, Wikipedia.
  • , 1920: Hydrocodone, a narcotic analgesic closely related to codeine is first synthesized in Germany. - 1920, Wikipedia.
  • 1930s: German patents from the middle 1930s indicate that oxymorphone as well as hydromorphone, hydrocodone, oxycodone, and acetylmorphone can be prepared—without the need for hydrogen gas—from solutions of codeine, morphine, and dionine by refluxing an acidic aqueous solution, or the precursor drug dissolved in ethanol, in the presence of Column 7 metals, namely palladium and platinum in fine powder or colloidal form or platina black. - Oxymorphone, Wikipedia.
  • 1938: The legal status of drug formulations originally sold between 1938 and 1962 - before FDA approval was required - was ambiguous. - Hydrocodone, Wikipedia.
  • 1955: The experiments in dogs conducted by Winder and Rosière in the mid-1950s reported in the Journal of Pharmacology in 1955 indicate that hydrocodone is 12 times stronger than codeine as an antitussive (morphine 14x, methadone 9x), and other tests from 1920 forward showed it was about six times stronger as an analgesic. - Hydrocodone, Wikipedia.
  • 1970: There are several conflicting views concerning the US availability of cough preparations containing ethylmorphine (also called dionine or codethyline) — Feco Syrup and its equivalents were first marketed circa 1895 and still in common use in the 1940s and 1950s, and the main ingredient is treated like codeine under the Controlled Substances Act of 1970. - Hydrocodone, Wikipedia.
  • 1971: In the UK, it is listed as a Class A drug under the Misuse of Drugs Act 1971. - Hydrocodone, Wikipedia.
  • 1990: Very dilute syrups of hydrocodone containing three or more other active ingredients were also Schedule V and often available without prescription until rescheduling to Schedule III circa or about 1990. - Diphenoxylate, Wikipedia.
  • 2001: Over a two month period during the summer of 2001, Lopez allowed Schwartz to use her name to fraudulently obtain prescriptions for the controlled substance hydrocodone. - Murder of Brian Stidham, Wikipedia.
  • October 3, 2003: The National Enquirer reported that Limbaugh was being investigated for illegally obtaining the prescription drugs oxycodone and hydrocodone. - Rush Limbaugh, Wikipedia.
  • 2006: In late 2006, the FDA began forcing the recall of many of these formulations due to reports of deaths in infants and children under the age of six. - Hydrocodone, Wikipedia.
  • 2006: [citation needed] The 2006 Physicians Desk Reference states that Norco 10, containing 10 milligrams of hydrocodone and 325 mg of APAP can be taken at a dosage of up to twelve tablets per day (120 mg of hydrocodone). - Hydrocodone, Wikipedia.
  • September 27, 2006: Some media outlets in Dallas reported on the morning of September 27, 2006 that Owens had tried to kill himself by intentionally ingesting an overdose of hydrocodone, a pain medication. - Terrell Owens, Wikipedia.
  • , 2007: Police also searched the home of freshman defensive end Brandon Joiner, and found marijuana, ecstasy, and hydrocodone. - 2007 Texas A&M Aggies football team, Wikipedia.
  • July 17, 2007: EDT on July 17, 2007, it was announced that three different drugs were found in Nancy Benoit's system: hydrocodone, hydromorphone and Xanax. - Chris Benoit double murder and suicide, Wikipedia.






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